Each year, TIME compiles a list of technological innovations it believes are making the world better and smarter. This year, four health-related devices with applications from the lab to the home made the cut.

Pocket-Sized Device that Sniffs Out Gluten

Coming in at number three on the 25-device list, was 6SensorLabs’ Nima, which aims to help people with celiac disease or gluten sensitivity by testing any food or drink for the protein in about two minutes.

“My hope is that people are going to be able to eat socially" without accidentally getting sick, Shireen Yeates, one of the company’s cofounders who is gluten-sensitive, told TIME. The device will begin shipping early next year.

Moving forward, the company plans to apply its technology to help detect other food allergens, such as peanuts and dairy.

A Smarter Stethoscope

Currently being tested in clinical trials, an electronic stethoscope attachment helps remove background noise and capture hard-to-hear heart and lung sounds, according to developers Connor Landgraf, Jason Bellet, and Tyler Crouch. It also collects and streams this data to the cloud where it can be synced with a patient’s electronic health record or analyzed using the companion app on a smartphone or tablet.

By saving this audio, doctors can compare it with previous recordings, potentially reducing the need for echocardiograms and other expensive tests. According to John Chorba, a cardiologist leading a trial of the device at the University of California, San Francisco, the device may help doctors detect murmurs, heart-valve abnormalities, and other conditions that “our ears are not able to."

Wearable Baby Monitor

This Fitbit-like device senses a baby’s heart rate, skin temperature, motion, and position while he or she sleeps and communicates this information to a mobile app, according to manufacturer Sproutling. The app lets parent know if their baby is sleeping soundly and provides information about the baby’s sleep habits and optimal sleep conditions. The $299 device was sold out at the time of this article’s publication.

Desktop DNA Lab

To compare DNA for bone marrow transplants or test potential treatments for genetic diseases, millions of strands of DNA are needed, which can take a full day to duplicate in a laboratory. Fluidigm says its device, which uses a new proprietary microchip, can amplify samples 1,000 times smaller than a drop of water and cut that to three hours with the touch of a button. The $120,000 device is being used in academic and research laboratories.